BROCHURE
Ghassem Amoabediny  is a Professor,University of Tehran,Iran

Ghassem Amoabediny

Professor

Organizing committee

Iran

University of Tehran

BIOGRAPHY

Prof. Dr. Amoabediny has an initial background in chemical engineering and graduated from university  Tehran  (Iran)  and  Technische  Hochschule  (RWTH)-Aachen  University  and  post doctorial from (RWTH)-Medical University (Germany) and Kaiserslautern (Germany). During his master and PhD he focused on the Biochemical Engineering –Biotechnology and during his post doctoral focused on Nano biotechnology and biomedical engineering.

 

He is a scientific member at the Department of Biotechnology and Pharmaceutical  Engineering Faculty of Chemical Engineering College of Engineering from 2001 to present at the University of Tehran. He is (co)author of over 200 scientific papers in international journals and conference records and holder of 06 patents/patent applications (more than 85 papers in International Journals and  06  international Congress and 06 national congresses).  He has several international projects with VUM Amsterdam,  (RWTH)-Aachen University,  Gent  University (Belgium) and also a collaboration with scientist from  York University of Canada.  

 

Also, he is Guest  Full Professor of Biomedical  /Nanobiotechnology at VUmc Amsterdam and a member of the joint nanobiotechnology group and administrator of bioreactor at VUMC-Amsterdam.  

 

He is editor of several international journals of Fermentation Technology and editorial board of Archives of Neuroscience and reviewer of Journal of Material Science and Engineering C. He has been manager  and  scientific  board  for  several  national  projects  on  the  basis  of  regenerative medicine,  bone tissue engineering,  lung tissue engineering,  artificial organs (lung,  kidney), nanobiosensors and nanobiofunctional particles for separation.

 

He has more than 06 national patents and 06  US patents which one of them has been granted.  He  was  as  an  assistant professor in University of Tehran in Department of Chemical Engineering from 2007 to 2010 and also Dean of Faculty of New Sciences and Technologies (FNST) from 2010 to 2012 in University of  Tehran and President  of  Science and Technology Park from 2008 to 2011 in University  of  Tehran  and  Vice  president  of  Research  from  2011  to  2014  in  University  of Tehran and Director of Research Centre of New Technologies in Life Science Engineering (UTLSE)  in  University  of  Tehran  and  professor  in  University  of  Tehran  Department  of Chemical Engineering from 2006 to present in university of Tehran.  

PUBLICATIONS

  1.  Mousavi, S. M., Towhidi, A., Zhandi, M., Amoabediny, G., Mohammadi-Sangcheshmeh, A., Sharafi, M., & Hussaini, S. M. H. Comparison of two different antioxidants in a nano lecithin-based extender for bull sperm cryopreservation. Animal reproduction science, 209, 106171. (2019).
  2. Ilanlou, S., Khakbiz, M., Amoabediny, G., & Mohammadi, J. Preclinical studies of acellular extracellular matrices as small-caliber vascular grafts. Tissue and Cell. (2019).
  3. Rajab, S., Babaeipour, V., Khanchezar, S., Amoabediny, G., Yazdian, F., & Mofid, M. R. Investigation of factors influencing oxygen content in Halobacterium salinarum growth medium for improved bacteriorhodopsin production. International Journal of Industrial Chemistry, 1-8. (2019).
  4. Derakhti,  S.,  Safiabadi-Tali,  S.  H.,  Amoabediny,  G.,  &  Sheikhpour,  M.  Attachment  and  detachment strategies  in  microcarrier-based  cell  culture  technology:  A  comprehensive  review.  Materials  Science  and Engineering: C, 109782. (2019).
  5. Haghiralsadat, B. F., Amoabediny, G., Naderinezhad, S., Morteza-Ratki, F., & Doulabi, B. Z. Formulation of a therapeutic cationic liposome-siRNA complex for development to fight osteosarcoma. Journal of Shahid Sadoughi University of Medical Sciences. (2019).
  6. Ilanlou,  S.,  Khakbiz,  M.,  Amoabediny,  G.,  Mohammadi,  J.,  &  Rabbani,  H.  Carboxymethyl  kappa carrageenan‐modified  decellularized  small‐diameter  vascular  grafts  improving  thromboresistance  properties. Journal of Biomedical Materials Research Part A. (2019).
  7. Khashayar,  P.,  Okhovat,  A.,  Adibi,  H.,  Windels,  J.,  Amoabediny,  G.,  Larijani,  B.,  &  Vanfleteren,  J. Numerical simulation of a multi-inlet microfluidic device for biosensing purposes in osteoporosis management. Journal of Diabetes & Metabolic Disorders, 1-8. (2019).
  8. Atapour, M., Amoabediny, G., & Ahmadzadeh-Raji, M. Integrated optical and electrochemical detection of Cu  2+  ions  in  water  using  a  sandwich  amino  acid–gold  nanoparticle-based  nano-biosensor  consisting  of  a transparent-conductive platform. RSC advances, 9(16), 8882-8893. (2019).
  9. Zamani,  Y.,  Mohammadi,  J.,  Amoabediny,  G.,  Visscher,  D.  O.,  Helder,  M.  N.,  Zandieh-Doulabi,  B.,  & Klein-Nulend, J. "Enhanced osteogenic activity by MC3T3-E1 pre-osteoblasts on chemically surface-modified poly (ε-caprolactone) 3D-printed scaffolds compared to RGD immobilized scaffolds." Biomedical Materials, 14(1), 015008. (2018).
  10. Adibfar,  A.,  Amoabediny,  G.,  Eslaminejad,  M.  B., Mohamadi, J.,  Bagheri,  F., &  Doulabi,  B.  Z.  "VEGF delivery by smart polymeric PNIPAM nanoparticles affects both osteogenic and angiogenic capacities of human bone marrow stem cells." Materials Science and Engineering: C, 93, 790-799. (2018).
  11. Haghiralsadat, F., Amoabediny, G., Naderinezhad, S., Forouzanfar, T., Helder, M. N., & Zandieh-Doulabi, B.  Preparation  of  PEGylated  cationic  nanoliposome-siRNA  complexes  for  cancer  therapy.  Artificial  cells, nanomedicine, and biotechnology, 46(sup1), 684-692. (2018).
  12. Mahfouzi, S. H., Amoabediny, G., Doryab, A., Safiabadi-Tali, S. H., & Ghanei, M. "Noninvasive Real-Time Assessment of Cell Viability in a Three-Dimensional Tissue." Tissue Engineering Part C: Methods, 24(4), 197- 204. (2018).
  13. Haghiralsadat, F., Amoabediny, G., Helder, M. N., Naderinezhad, S., Sheikhha, M. H., Forouzanfar, T., & Zandieh-doulabi,  B.  "A  comprehensive  mathematical  model  of  drug  release  kinetics  from  nano-liposomes, derived  from  optimization  studies  of  cationic  PEGylated  liposomal  doxorubicin  formulations  for  drug-gene delivery." Artificial cells, nanomedicine, and biotechnology, 46(1), 169-177. (2018).
  14. Amoabediny,  G.,  Haghiralsadat,  F.,  Naderinezhad,  S.,  Helder,  M.  N.,  Akhoundi  Kharanaghi,  E., Mohammadnejad Arough, J., & Zandieh-Doulabi, B. (2018). "Overview of preparation methods of polymeric and lipid-based (niosome, solid lipid, liposome) nanoparticles: A comprehensive review." International Journal of Polymeric Materials and Polymeric Biomaterials, 67(6), 383-400. (2018). 
  15. Haghiralsadat, F., Amoabediny, G., Naderinezhad, S., Nazmi, K., De Boer, J. P., Zandieh-Doulabi, B. ... & Helder, M. N. "EphA2 Targeted Doxorubicin-Nanoliposomes for Osteosarcoma Treatment." Pharmaceutical research, 34(12), 2891-2900. (2017).
  16. Khashayar, P., Amoabediny, G., Larijani, B., Hosseini, M., & Vanfleteren, J. "Fabrication and Verification of  Conjugated  AuNP-Antibody  Nanoprobe  for  Sensitivity  Improvement  in  Electrochemical  Biosensors." Scientific reports, 7(1), 16070. (2017). 
  17. Rahmani, S, Tabandeh, F, Faghihi, S, Amoabediny, G, Shakibaie, M, Noorani, B, Yazdian, F.” Fabrication and characterization of poly(epsilon-caprolactone)/gelatin nanofibrous scaffolds for retinal tissue engineering”. INTERNATIONAL  JOURNAL  OF  POLYMERIC  MATERIALS  AND  POLYMERIC  BIOMATERIALS (2017).
  18. Salehi‐Nik, Nasim, Seyedeh Parnian Banikarimi, Ghassem Amoabediny, Behdad Pouran, Mohammad Ali Shokrgozar, Behrouz Zandieh‐Doulabi, and Jenneke Klein‐Nulend. "Flow Preconditioning of Endothelial Cells on  Collagen‐Immobilized  Silicone  Fibers  Enhances  Cell  Retention  and  Antithrombotic  Function."  Artificial organs 41, no. 6 (2017).
  19. Khashayar,  Patricia,  Ghassem  Amoabediny,  Morteza  Hosseini,  Rik  Verplancke,  Farideh  Razi,  Jan Vanfleteren, and Bagher Larijani. "An electrochemical biosensor based on AuNP-modified gold electrodes for selective determination of serum levels of osteocalcin." IEEE Sensors Journal 17, no. 11 (2017).
  20. Haghiralsadat, F., Amoabediny, G., Sheikhha, M. H., Zandieh‐doulabi, B., Naderinezhad, S., Helder, M. N., & Forouzanfar, T. "New liposomal doxorubicin nanoformulation for osteosarcoma: Drug release kinetic study based on thermo and pH sensitivity." Chemical biology & drug design (2017).
  21. Amoabediny, G., Sheikhha, M. H., Forouzanfar, T., Helder, M. N., & Zandieh-doulabi, B. "A novel approach on drug delivery: Investigation of new nano-formulation of liposomal doxorubicin and biological evaluation of entrapped doxorubicin on various osteosarcomas cell lines." Cell J (Yakhteh) 19.1 (2017). 
  22. Salehi-Nik,  N.,  Malaie-Balasi,  Z.,  Amoabediny,  G.,  Banikarimi,  S.  P.,  Zandieh-Doulabi,  B.,  &  Klein- Nulend,  J.  "Sustained  release  of  growth  hormone  and  sodium  nitrite  from  biomimetic  collagen  coating immobilized on silicone tubes improves endothelialization." Materials Science and Engineering: C (2017).
  23. Hasanzadeh, E, Amoabediny, G, Haghighipour, N, Gholami, N, Mohammadnejad, J, Shojaei, S, Salehi-Nik, N. “The stability evaluation of mesenchymal stem cells differentiation toward endothelial cells by chemical and mechanical stimulation”. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2017). 
  24. Khashayar, P., Amoabediny, G., Hosseini, M., Verplancke, R., Razi, F., Vanfleteren, J., & Larijani, B. "A highly sensitive electrochemical biosensor based on AuNP-modified gold electrodes for selective determination of serum levels of osteocalcin." IEEE Sensors Journal (2017). 
  25. Doryab,  A.,  Heydarian,  M.,  Amoabediny,  G.,  Sadroddiny,  E.,  &  Mahfouzi,  S.  "Recellularization  on Acellular Lung Tissue Scaffold Using Perfusion-Based Bioreactor: An Online Monitoring Strategy." Journal of Medical and Biological Engineering 37.1 (2017). 
  26. Maghsoudi, A., Yazdian, F., Shahmoradi, S., Ghaderi, L., Hemati, M., & Amoabediny, G. "Curcumin-loaded polysaccharide  nanoparticles:  Optimization  and  anticariogenic  activity  against  Streptococcus  mutans." Materials Science and Engineering: C 75 (2017).
  27. Khashayar,  P.,  Amoabediny,  G.,  Larijani,  B.,  Hosseini,  M.,  Verplancke,  R.,  Schaubroeck,  D.,  ...  & Goemaere,  S.  "A  Multiplexed  Microfluidic  Platform  for  Bone  Marker  Measurement:  A  Proof-of-Concept." Micromachines 8.5 (2017). 
  28. Pesaran,  M.,  and  GH  Amoabediny.  "Study  on  the  stability  and  reusability  of  Glutamate  Dehydrogenase immobilized on bacterial cellulose nanofiber." Fibers and Polymers 18.2 (2017).
  29. Haghiralsadat,  F.,  Amoabediny,  G.,  Sheikhha,  M.  H.,  Naderinezhad,  S.,  Malaei-Balasi,  Z.,  &  Zandieh Doulabi, B. "New Approach for the Synthesis, Entrapment of Hydrophilic Drugs and Evaluation of Physico- Chemical Characteristics of PH-sensitive Nano-Liposome: Improving Therapeutic Efficacy of Doxorubicin in Order to Treatment Bone Tumor and Reducing the Side Effects of Doxorubicin." SSU_Journals 24.10 (2017).
  30. Zabihi, A., Akhondzadeh Basti, A., Amoabediny, G., Khanjari, A., Tavakkoly Bazzaz, J., Mohammadkhan, F. ... & Vanaki, E. "Physicochemical Characteristics of Nanoliposome Garlic (Allium sativum L.) Essential Oil and  Its  Antibacterial  Effect  on  Escherichia  coli  O157:  H7."  Journal  of  food  quality  and  hazards  control  4.1 (2017).
  31. Mohammad  Mahdi  Ochi,  Ghasem  Amoabediny,  Seyed  Mahdi  Rezayat,Azim  Akbarzadeh,  Bahman Ebrahimi," In Vitro Co-Delivery Evaluation of Novel Pegylated Nano-Liposomal Herbal Drugs of Silibinin and Glycyrrhizic Acid (Nano-Phytosome) to Hepatocellular Carcinoma Cells", CELL JOURNAL(Yakhteh), 18(2): 135-148, 2016.
  32. Patricia Khashayar, Ghassem Amoabediny, Bagher Larijani, Jan Vanfleteren, "Bone biosensors: knowing the present and predicting the future", Journal of Micromechanics and Microengineering, 023002 (7pp), 2016.
  33. Nasim Salehi-Nik, Seyedeh Parnian Banikarimi, Ghassem Amoabediny, Behdad Pouran, Mohammad Ali Shokrgozar, Behrouz Zandieh-Doulabi, Jenneke Klein-Nulend, "Flow Preconditioning of Endothelial Cells on CollagenImmobilized  Silicone  Fibers  Enhances  Cell  Retention  and  Antithrombotic  Function",  Artificial Organs, Vol. 00, No. 00, 2016.
  34.  Nasim  Salehi-Nik,  Ghassem  Amoabediny,  Seyedeh  Parnian  Banikarimi,  Behdad  Pouran,  Zahra  Malaie- Balasi,  Behrouz  Zandieh-Doulabi,  Jenneke  Klein-Nulend,  "Nanoliposomal  Growth  Hormone  and  Sodium Nitrite  Release  from  Silicone  Fibers  Reduces  Thrombus  Formation  Under  Flow",  Annals  of  Biomedical Engineering, 2016.
  35. Fatemeh Mokhtari-Jafari, Ghassem Amoabediny, Nooshin Haghighipour, Reza Zarghami, Alireza Saatchi, Javad Akbari, Nasim Salehi-Nik, "Mathematical modeling of cell growth in a 3D scaffold and validation of static and dynamic cultures", Engineering in life science, 16, 290-298, 2016.
  36. Ali  Doryab,  Ghassem  Amoabediny,  Amir  Salehi-Najafabadi,  "Advances  in  pulmonary  therapy  and  drug development: Lung tissue engineering to lung-on-a-chip", Biotechnology Advances, 2016.

and many more

EDUCATION

  1. Bachelor degree - Chemical Engineering from University of Tehran, Iran
  2. Master degree - Chemical Engineering-Biotechnology from University of Tehran, Iran
  3. PhD degree  - Rheinisch-Westfälische Technische Hochschule (RWTH)-Aachen 

RESEARCH INTEREST

  • Regenerative Medicine
  • Bone Tissue Engineering
  • Lung Tissue Engineering
  • Artificial Organs (lung,  kidney)
  • Nanobiosensors and Nanobiofunctional particles for separation
  • Millibioreactor
  • Microbioreactor
  • Nanobioreactor
  • Decellularization and recellularization soft tissues using bioreactor
  • Bioreactor for stem-cell production
  • Nano liposome Producer
  • Several Liposomal Products (such as: Liposomal Amphotericin B/ Fe/ VEGF/ Zinc/ Doxorubicin/ 
  • Nanobioseparator
  • Out-of-Body-Artificial lung, Oxygenator
  • Phosphatidylcholine
  • Biosensors
  • Artificial Blood 

HONORS AND AWARDS

  • 2019  Selected  as  sixth  place  at  the  first  national  event  designing  and  manufacturing  rapid  detection sensors at the Vice Presidential Office of Science and Technology, Biotech Staff, Iran.
  • 2018  Successful faculty member in gaining international status, University of Tehran, Iran.
  • 2015  University  of  Tehran  Award  for  Innovation,  “New  device  for  nano-bioseparator  device  based  on nano-magneto particles for biofluidics”, 15th Research Festival  of University of Tehran,  Iran,  80th Anniversary of University of Tehran 
  •  2013  University  of  Tehran  Award  for  Excellence  in  Coordination  of  International  (European)  Scientific Collaboration, International Festival, Iran 
  • 2011  Project  award,  L.B.N.  Sina  Festival,  ex  vivo  artificial  lung,  Medical  Sciences  Tehran  University (MSTU), Iran 
  • 2010  Minister of Science and Technology Project award, 11th festival of celebration of top researchers and technologists, national project of targeted drug delivery to cancer cells, Iran  
  • 2010  Vice-president  in  Science  and  Technology  (Iran)  selected  technological  achievements  on  knowledge for production of nano-drugs based on nano-liposome technology, Iran   
  • 2009  Shahid Chamran Prize for micro-bioreactor project, Innovation and Technology Entrepreneurship Festival, University of Tehran, Iran  
  • 2007  Innovation  project  selected  by  1)  the  Vice-president  in  Science  and  Technology  (Iran), “technological project of milli-bioreactor”, and 2) University of Tehran, Iran  
  • 1993  First rank in bachelor studies, University of Tehran, Iran (#1 in Chemical Engineering)  

COLLABORATIONS

  1. Development of large bone tissue: Development of large 3D bone tissue constructs by integration of cells on 3D scaffolds in intelligent bioreactors, 2015,  VU University Medical Center Amsterdam and Academic Center for Dentistry (ACTA) Amsterdam. 
  2. Treatment  of  osteosarcoma  metastases:  Design  preparation  of  siRNA  and  doxorubicin  loaded  Nano- liposomes  in  order  to  targeted  delivery  to  osteosarcoma  cell  line,  2014.  VU  University  Medical Center Amsterdam and Academic Center for Dentistry (ACTA) Amsterdam.
  3. Performance  of  portable  artificial  kidney:  investigation  on  the  performance  nano-biodialyzer  system  for  a portable  artificial  kidney,  2014-present  (Prof.dr.  K.  Mottaghy,  Dept  Physiol,  RWTH  Aachen  University, Germany) 
  4. Simulation  and  experimental  methods  for  optimizing  oxygenator  performance,  2007-2013,  Prof.dr.  K. Mottaghy, Dept Physiol, RWTH Aachen University, Germany). 
  5. Access to knowledge-technical manufacture nano-systems, nano-bio-sensors for diagnosis of osteoporosis, 2013-present (Prof.dr. Iahn, University of Ghent, Belgium) 
  6. Access to technical knowledge and design of novel nanobiosensor for detection of metastasic cancer cells, 2010-2014 (Dr. E. Ghafarzadeh: Dept Electr Engin & Computer Sci, York University, Toronto, Canada)