BROCHURE
Prof. Haseeb A. Khan is a Distinguished Professor,King Saud University,Saudi Arabia

Prof. Haseeb A. Khan

Distinguished Professor

Organizing committee

Saudi Arabia

King Saud University

BIOGRAPHY

Dr. Haseeb A. Khan is a Distinguished Professor and Group Leader at the Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia. He is the Chair Professor at Research Chair for Biomedical Applications of Nanomaterials. Before moving to King Saud University, he served as a Senior Scientist at Armed Forces Hospital, Riyadh, Saudi Arabia. He obtained his PhD from Aligarh Muslim University (a central government university), Aligarh, India and received scientific trainings at USA, UK, France, Denmark and Finland. He is a Fellow of the Royal College of Pathologists (UK) and the Royal Society of Chemistry (UK). He has published over 300 articles, authored 2 books and 19 book chapters. He has deposited 210 gene sequences to GenBank and 13 SNPs to dB-SNP database. His innovative research includes the development of methods and protocols for the analysis of ATP, GFAP and tyrosine hydroxylase in mouse brain; efficient extraction of skin lipids; and computer-aided quantification of gastric ulcers in rats. He has also developed 8 software tools for biomedical applications, which have been published in reputed journals and demanded by more than 400 scientists from 40 countries. Scientists from prestigious institutions like Harvard University, Oxford University, WHO, etc have appreciated these software tools. The factorial equation developed by him has been utilized by scientists from Emory University, USA and Swinburne University, Australia for creating their own software tools. He is a recipient of Microsoft eScience Award.

PUBLICATIONS

Selected Publication (from >300) 1. Alrashood ST, Elrobh MS, Alamery S, Odeibat HA, Khan HA. A short review of biochemical mechanisms in iminodipropionitrile-induced movement disorder. Neurochem J. 2020 (Accepted). 2. Murugaiah V, Varghese PM, Saleh SM, Tsolaki AG, Alrokayan SH, Khan HA, Collison KS, Sim RB, Nal B, Al-Mohanna FA, Kishore U. Complement-independent modulation of influenza A virus infection by Factor H. Front Immunol. 2020 (Accepted). 3. Khan HA, Ibrahim KE, Alrashood ST, Alamery S, Alrokayan SH, Al-Harbi N, Al-Mutary MG, Sobki SH, Khan I. Immunohistochemistry of IL-1b, IL-6 and TNF-a in spleen of mice treated with gold nanoparticles. Saudi J Biol Sci. 2020 (Accepted). 4. Al-Harbi NS, Alrashood ST, Siddiqi NJ, Arafah MM, Ekhzaimy A, Khan HA. Effect of naked and PEG-coated gold nanoparticles on histopathology and cytokines expression in rat liver and kidneys. Nanomedicine (Lond). 2020; 15 (3): 289-302. 5. Khan HA. Importance of customized (task oriented) software tools for biomedical applications. Bioinformation. 2020; 16 (1): 30-33. 6. Ashraf R, Sofi HS, Akram T, Rather HA, Abdal-Hay A, Shabir N, Vasita R, Alrokayan SH, Khan HA, Sheikh FA. Fabrication of multifunctional cellulose/TiO(2)/Ag composite nanofibers scaffold with antibacterial and bioactivity properties for future tissue engineering applications. J Biomed Mater Res A. 2020. doi: 10.1002/jbm.a.36872. 7. Al-Obaida MI, Al-Nakhli AKM, Arif IA, Faden A, Al-Otaibi S, Al-Eid B, Ekhzaimy A, Khan HA. Molecular identification and diversity analysis of dental bacteria in diabetic and non-diabetic females from Saudi Arabia. Saudi J Biol Sci. 2020; 27(1): 358-362. 8. Abdullah NA, Asib NAM, Aziz NAA, Umbaidilah SZ, Soga T, Alrokayan SAH, Khan HA, Mahmood MR, Khusaimi Z. Evaluation of the crystalline structure of Ag+-doped ZnO thin film treated with selected annealing temperatures. Jpn J Appl Phys. 2020; 59 (SAAC12), 1-8. 9. Asib NAM, Afaah AN, Aadila A, Husairi FS, Alrokayan SAH, Khan HA, Mamat MH, Soga T, Rusop M, Khusaimi Z. Solution growth of highly crystalline and dense-packed ZnO nanorods on a TiO2 seed layer with enhanced absorbance properties. Jpn J Appl Phys. 2020; 59 (SAAC10), 1-7. 10. Umbaidilah SZ, Asib NAM, Abdullah NA, Soga T, Alrokayan SAH, Khan HA, Asli NA, Rusop M, Khusaimi Z. The effect of silver doped in zinc oxide nanorods on titanium dioxide seeded substrate synthesized by binary solution technique. Jpn J Appl Phys. 2020; 59 (SAAC08), 1-7. 11. Alwelaie MA, Al Mutary MG, Siddiqi NJ, Arafah MM, Alhomida AS, Khan HA (2019) Time-course evaluation of iminodipropionitrile-induced liver and kidney toxicities in rats: a biochemical, molecular and histopathological study. Dose Response. 17 (2), 1559325819852233. 12. Patel M, Siddiqi NJ, Sharma P, Alhomida AS, Khan HA (2019) Reproductive toxicity of pomegranate peel extract synthesized gold nanoparticles: A multi-generation study in C. elegans. J. Nanomaterial. 2019. 8767943. 13. Mallhi ZI, Rizwan M, Mansha A, Ali Q, Asim S, Ali S, Hussain A, Alrokayan SH, Khan HA, Alam P, Ahmad P (2019). Citric Acid Enhances Plant Growth, Photosynthesis, and Phytoextraction of Lead by Alleviating the Oxidative Stress in Castor Beans.Plants (Basel) 19;8(11). pii: E525. 14. Khan HA, Alamery S, Ibrahim KE, El-Nagar DM, Al-Harbi N, Rusop M, Alrokayan SH (2019) Size and time-dependent induction of proinflammatory cytokines expression in brains of mice treated with gold nanoparticles. Saudi J Biol Sci. 26:625-631. 15. DeCordova S, Abdelgany A, Nayak A, Walker T, Shastri A, Alrokayan SH, Khan HA, Singh S, Sim R, Pennington ND, Murugaiah V, Pathan A, Kishore U (2019) Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients. Immunobiology. DOI: 10.1016/j.imbio.2019.07.006 16. Thakur G, Prakash G, Murthy V, Sable N, Menon S, Alrokayan S, Khan HA, Murugaiah V, Bakshi G, Kishore U, Madan T (2019) Human SP-D acts as an innate immune surveillance molecule against androgen-responsive and androgen-resistant prostate cancer cells. Front. Oncol. 9, 565. 17. Rani RA, Zoolfakar AS, Ryeeshyam MFM, Ismail AS, Mamat MH, Alrokayan S, Khan HA, Kalantar-zadeh K, Mahmood MR (2019) High surface area to volume ratio 3D nanoporous Nb2O5 for enhanced humidity sensing. J. Electron. Mater. 48 (6), 3805-3815. 18. Sulimai NH, Rani RA, Khusaimi Z, Abdullah S, Salifairus MJ, Alrokayan S, Khan HA, Sermon PA, Rusop M (2019) Facile synthesis of CaCO3 and investigation on structural and optical properties of high purity crystalline calcite. Mater. Sci. Eng. B. 243, 78-85. 19. Al-Obaida MI, Al-Nakhli AK, Arif IA, Faden A, Al-Otaibi S, Al Eid B, Al Ekhzaimy A, Khan HA (2019) Molecular identification and diversity analysis of dental bacteria in diabetic and non-diabetic females from Saudi Arabia. Saudi J. Biol. Sci. 27 (1), 358-362. 20. Almusawi MA, Gosadi I, Abidia R, Almasawi M, Khan HA (2018) Potential risk factors for dental caries in type-2 diabetes patients. Int. J. Dent. Hyg. 16 (4): 467-475. 21. Ibrahim KE, Al Mutary MG, Bakhiet AO, Khan HA (2018) Histopathology of the liver, kidney, and spleen of mice exposed to gold nanoparticles. Molecules. 23, 1848, 1-14. 22. Bhat GA, Khan HA, Alhomida AS, Sharma P, Singh R; Paray BA (2018) GLP-I secretion in healthy and diabetic Wistar rats in response to aqueous extract of Momordica charantia. BMC Comp. Alter. Med. 18; 18(1): 162. 23. AL-Asmari AK, Khan HA, Manthiri RA, Al-Khlaiwi AA, Al-Asmari BA, Ibrahim KE (2018) Protective effect of the natural herbal compound quercetin against snake venom-induced hepatic and renal toxicities in rats. Food Chem. Toxicol. 118: 105-110. 24. Sakharkar MK, Rajamanickam K, Chandra R, Khan HA, Alhomida AS, Yang J (2018) Identification of novel drug targets in bovine respiratory disease: an essential step in applying biotechnological techniques to develop more effective therapeutic treatments. Drug Des. Dev. Ther. 12: 1135-1146. 25. Ibrahim KE, Bakhiet AO, Awadalla ME, Khan HA (2018) A priming dose protects against gold nanoparticles-induced proinflammatory cytokines mRNA expression in mice. Nanomedicine (Lond). 13(3), 313-323. 26. Khan HA, Sobki SH, Ekhzaimy A, Khan I, Almusawi MA (2018) Biomarker potential of C-peptide for screening of insulin resistance in diabetic and non-diabetic individuals. Saudi J. Biol. Sci. doi.org/10.1016/j.sjbs.2018.05.027 27. Khan HA, Ibrahim KE, Khan A, Alrokayan SH, Alhomida AS (2017) Immunostaining of proinflammatory cytokines in renal cortex and medulla of rats exposed to gold nanoparticles. Histol. Histopathol. 32, 597-607. 28. Chen L, Krol ES, Sakharkar MK, Khan HA, Alhomida AS, Yang J (2017) Residues His172 and Lys238 are essential for the catalytic activity of the maleylacetate reductase from Sphingobium chlorophenolicum strain L-1. Sci. Rep. 7, 18097, 1-11. 29. Khan HA (2017) Current trends for customized biomedical software tools. Bioinformation, 13 (12), 402-404. 30. Nafiujjaman M, Khan HA, Lee Y (2017) Peptide-influenced graphene quantum dots on iron oxide nanoparticles for dual imaging of lung cancer cells. J. Nanosci. Nanotechnol. 17 (3), 1704-1711. 31. Khan HA, Ekhzaimy A, Khan I, Sakharkar M (2017) Potential of lipoproteins as biomarkers in acute myocardial infarction. Anatolian J. Cardiol. 18, 68-74. 32. Pondman KM, Paudyal B, Sim RB, Kaur A, Kouser L, Tsolaki AG, Jones LA, Salvador-Morales C, Khan HA, Haken B T, Stenbeck G, Kishore U (2017) Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Nanoscale. 9 (3), 1097-1109. 33. Khan HA, Ibrahim KE, Khan A, Alrokayan SH, Alhomida AS (2016) Comparative evaluation of immunohistochemistry and real-time PCR for measuring proinflammatory cytokines gene expression in livers of rats treated with gold nanoparticles. Exp. Toxicol. Pathol. 68 (7):381-390. 34. Khan HA (2016) Lipoprotein(a) as a biomarker for risk stratification of acute myocardial infarction. Ann. Clin. Exp. Metab. 1 (1), 1004. 35. Sherwani SI, Khan HA, Ekhzaimy A, Masood A, Sakharkar MK (2016) Significance of HbA1c test in diagnosis and prognosis of diabetic patients. Biomarker Insight. 11, 95-104. 36. Kouser L, Abdul-Aziz M, Tsolaki AG, Singhal D, Khan HA, Sim RB, Kishore U (2016) A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway. Mol. Immunol. 73, 76-87. 37. Khan HA (2015) Impaired nerve conduction velocity in MPTP-treated mouse model of Parkinson's disease. Int. J. Neurosci. 125 (5), 361-366. 38. Nafiujjaman M, Nurunnabi M, Kang SH, Reeck G, Khan HA, Lee Y (2015) Ternary graphene quantum dot-polydopamine-Mn3O4 nanoparticles for optical imaging guided photodynamic therapy and T1-weighted magnetic resonance imaging. J. Mater. Chem. B. 3, 5815-5823. 39. Khan HA, Ibrahim KE (2015) Pattern of neurobehavioral and organ-specific toxicities of ?, ?'-iminodipropionitrile in mice. Arch. Med. Sci. 11 (5), 1137-1144. 40. Khan HA, Shanker R (2015) Toxicity of nanomaterials. Biomed. Res. Int. doi: 10.1155/2015/521014 41. Pondman KM, Pednekar L, Paudyal B, Tsolaki AG, Kouser L, Khan HA, Shamji MH, Haken BT, Stenbeck G, Sim RB, Kishore U (2015) Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes. Nanomedicine. 11 (8), 2109-2118. 42. Khatun Z, Nurunnabi M, Nafiujjaman M, Reeck G, Khan HA, Cho KJ, Lee Y (2015) A hyaluronic acid nanogel for photo-chemo theranostic of lung cancer with simultaneous light-responsive controlled release of doxorubicin. Nanoscale. 7 (24):10680-10689. 43. Nurunnabi M, Parvez K, Nafiujjaman M, Revuri V, Khan HA, Feng X, Lee Y (2015) Bioapplication of graphene oxide derivatives: drug/gene delivery, imaging, polymeric modification, toxicology, therapeutics and challenges. RSC Advances. 5, 42141-42161. 44. Sherwani SE, Khan HA (2015) Role of 5-hydroxymethylcytosine in neurodegeneration. Gene 570 (1): 17-24. 45. Khan HA, Sobki SH, Alhomida AS (2015) Regression analysis for testing association between fasting blood sugar and glycated hemoglobin in diabetic patients. Biomed. Res. 26 (3), 604-606. 46. Al Asmari A, Khan HA, Manthiri RA, Al Yahya KM, Al Otaibi KE (2014) Effects of Echis Pyramidum snake venom on hepatic and renal antioxidant enzymes and lipid peroxidation in rats. J. Biochem. Mol. Toxicol. 28 (9), 407-412. 47. Ibrahim KE, Khan HA, Omer FA (2014) Histological insights in iminodipropionitrile-induced toxicity in rats. Exp. Toxicol. Pathol. 66 (2-3), 89-96. 48. Islam S, Yakout SM, Al Daghri NM, Alhomida AS, Khan HA (2014) Serum levels of thrombotic markers in patients with acute myocardial infarction. Int. J. Clin. Exp. Med. 7(4):1059-1063. 49. Khan HA, Arif IA, Sudimack AG, Williams JB (2014) Cytotoxic effects of cadmium and paraquat on avian skin fibroblasts. Ann. Res. Rev. Biol. 4 (11), 1757-1768. 50. Khan HA, Ola MS, Alhomida AS, Sobki SH, Khan SA (2014). Evaluation of HbA1c criteria for diagnosis of diabetes mellitus: a retrospective study of 12785 type 2 Saudi male patients. Endocrine Res. 39 (1):61-65. 51. Khan HA, Arif IA, Williams JB, Champagne AM, Shobrak M (2014) Skin lipids from Saudi Arabian birds. Saudi J Biol Sci. 21 (1), 173-177. 52. Khan HA (2013) A novel gene expression index (GEI) with software support for comparing microarray gene signatures. Gene 512 (1), 82-88. 53. Khan HA, Alhomida AS (2013) Single nucleotide polymorphism in CPT1B and CPT2 genes and its association with blood carnitine levels in acute myocardial infarction patients. Gene 523:76-81. 54. Khan HA, Alhomida AS, Al Madani H, Sobki SH (2013) Carnitine and acylcarnitine profiles in dried blood spots of patients with acute myocardial infarction. Metabolomics 9, 828-838. 55. Khan HA, Abdelhalim MA, Alhomida AS, Al Ayed MS (2013) Effects of naked gold nanoparticles on proinflammatory cytokines mRNA expression in rat liver and kidney. Biomed. Res. Int. 2013:590730. 56. Khan HA, Alhomida AS, Ola MS, Sobki SH (2013) Alterations in prothrombin time and activated partial thromboplastin time in patients with acute myocardial infarction. Int. J. Clin. Exp. Med. 6(4):294-7. 57. Khan HA, Abdelhalim MA, Alhomida AS, Al Ayed MS (2013) Transient increase in IL-1?, IL-6 and TNF-? genes expression in liver of rats exposed to gold nanoparticles. Genet. Mol. Res. 12 (4), 5851-5857. 58. Khan HA, Alhomida AS, Sobki SH, Habib SS, Al Aseri Z, Khan AA, Al Moghairi A (2013) Serum markers of tissue damage and oxidative stress in patients with acute myocardial infarction. Biomed. Res. 24 (1), 15-20. 59. Khan HA, Alhomida AS, Sobki SH (2013). Lipid profile of patients with acute myocardial infarction and its correlation with systemic inflammation. Biomarker Insight. 8, 1-7. 60. Khan HA, Arif IA (2013) COI barcodes and phylogeny of doves (Columbidae family). Mito. DNA. 24 (6), 689-696.

EDUCATION

• Ph. D. (1989), Analytical Biochemistry, Aligarh Muslim University, Aligarh, India. The Thesis has been recognized and deposited in the online repository of National ‘ShodhGanga’ Project. • M. Phil. (1986), Analytical Biochemistry, Aligarh Muslim University, Aligarh, India. • M. Sc. (1983), Chemistry, Rohilkhand University, Bareilly, India. • B. Sc. (1978), Chemistry, Zoology, Botany, Rohilkhand University, Bareilly, India.

RESEARCH INTEREST

• Biomedical Sciences (disease biomarkers, clinical biochemistry, inflammation, metabolomics, neurodegeneration, animal models, pharmacology, toxicology, molecular genetics) • Nanomedicine (immunological response of nanomaterials, safety and biocompatibility, biochemical interactions, targeted drug delivery, diagnostic potential of nanomaterials) • Animal Biotechnology (cytotoxicity assays, cellular responses to environmental stressors, oxygen consumption rate, DNA barcoding, molecular conservation) • Bioinformatics (biomedical software development, evolutionary bioinformatics, microarray data analysis, phylogenetic analysis)

HONORS AND AWARDS

• Smart Clients for eScience Award from Microsoft Corporation, USA (2006).
• Indian Overseas Best Faculty Award, GISR Foundation, Noida, India (2019)
• Achievement Award from College of Science, King Saud University, Saudi Arabia (2013) • Achievement Award from the Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia (2012)
• Achievement Award from Saudi Biological Society, Riyadh, Saudi Arabia (2012).
• Achievement Award from Saudi Biological Society, Riyadh, Saudi Arabia (2011).
• Certificate of Appreciation from the Research Center, Armed Forces Hospital, Riyadh (2004).
• Scientific Achievement Award from Department of Postgraduate and Academic Affairs, Armed Forces Hospital, Riyadh, Saudi Arabia (2000).
• Foreign Travel Grant from CSIR, New Delhi to participate in IAWPRC/IWSA conference on Nitrogen Pollution of Water, held at Brussels, Belgium, 12-19 November, 1987.
• Senior Research Fellowship by the Council of Scientific and Industrial Research (CSIR), New Delhi, India form 1 March 1988 to 28 February 1990.
• Junior and Senior Research Fellowships by the University Grants Commission (UGC), New Delhi, India from 16 August 1985 to 29 February 1988.

COLLABORATIONS

• Ohio State University, Columbus, USA
• University of Saskatchewan, Canada
• Brunel University, London, UK
• Korea National University of Transportation, Chungju, South Korea
• University of Technology, Shah Alam, Selangor, Malaysia
• Prince Sultan Military Medical City, Riyadh, Saudi Arabia
• King Khalid University Hospital, Riyadh, Saudi Arabia
• Jawaharlal Nehru Institute of Advanced Studies, Hyderabad, India
• Indian Institute of Chemical Technology, Hyderabad, India

EDITORSHIP

• Frontiers in Bioscience, FIB Publications, USA.
• International Journal of Clinical & Experimental Medicine, eCentury Publishing, USA.
• Peer J, PeerJ Inc., Corte Madera, CA, USA.
• Current Nanomedicine, Bentham Science Publishers, UAE.
• Bioinformation, Biomedical Informatics Publishers, Singapore.
• World Journal of Experimental Medicine, Baishideng Publishing Group, China.
• Saudi Journal of Biological Sciences, Saudi Biological Society, Saudi Arabia.
• Biomedical Research, Allied Academies, USA.
• Biomed Research International, Lead Guest Editor, Hindawi Publishing Corp., USA.
• Animal Biology Journal, Nova Science Publishers, USA.
• International Journal of Neurology Research, Sheung Wan, Hong Kong.
• Biosciences, Biotechnology Research Asia, Oriental Science Publishers, India.